Human papillomavirus and cervical cancer risk perception and vaccine acceptability among adolescent girls and young women in Durban, South Africa

被引：8

作者：

Russell, V. L. ^{[1
]}

Ogilvie, G. ^{[2
,3
]}

Beksinska, M. ^{[4
]}

Nyirenda, M. ^{[5
,6
]}

Mitchell-Foster, S. ^{[7
]}

Lavoie, J. ^{[1
,8
]}

Harder, H. ^{[9
]}

Wood, B. ^{[10
]}

Smith, P. ^{[11
]}

Dietrich, J. J. ^{[12
,13
]}

Smit, J. ^{[4
]}

Brockman, M. A. ^{[11
]}

Grag, G. ^{[14
]}

Kaida, A. ^{[11
]}

机构：

[1] Univ Manitoba, Fac Hlth Sci, Winnipeg, MB, Canada

[2] Univ British Columbia, Sch Populat & Publ Hlth, Fac Med, Vancouver, BC, Canada

[3] British Columbia Ctr Dis Control, Vancouver, BC, Canada

[4] Univ Witwatersrand, Dept Obstet & Gynaecol, MRU MatCH Res Unit, Fac Hlth Sci, Durban, South Africa

[5] South African Med Res Council, Burden Dis Res Unit, Cape Town, South Africa

[6] Univ KwaZulu Natal, Sch Nursing & Publ Hlth, Coll Hlth Sci, Durban, South Africa

[7] Univ British Columbia, Fac Med, Vancouver, BC, Canada

[8] Univ Manitoba, Ongomiizwin Indigenous Inst Hlth & Healing, Winnipeg, MB, Canada

[9] Univ Northern British Columbia, Fac Hlth Sci, Prince George, BC, Canada

[10] Univ Ottawa, Sch Epidemiol & Publ Hlth, Fac Med, Ottawa, ON, Canada

[11] Simon Fraser Univ, Fac Hlth Sci, Burnaby, BC, Canada

[12] Univ Witwatersrand, Perinatal HIV Res Unit, Fac Hlth Sci, Johannesburg, South Africa

[13] South African Med Res Council, Hlth Syst Res Unit, Cape Town, South Africa

[14] South African Med Res Council, Off President, Cape Town, South Africa

来源：

SAMJ SOUTH AFRICAN MEDICAL JOURNAL | 2020年 / 110卷 / 09期

基金：

英国医学研究理事会; 加拿大健康研究院;

关键词：

HPV VACCINATION; HIV; SAFETY; HEALTH;

D O I：

10.7196/SAMJ.2020.v110i9.14367

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background. The relationship between HIV and cervical cancer is well established. Interventions that focus on creating human papillomavirus (HPV) vaccine and cervical cancer prevention messaging for adolescents, caregivers and educators will increase uptake of HPV vaccinations, HPV testing and cervical cancer screening for high-risk adolescent girls and young women (AGYW). In order to effectively develop appropriate interventions, it is important to examine AGYW's perceptions regarding their personal risk of acquiring HPV, as well as vaccine acceptability. Objectives. To measure the level of perceived personal risk of acquiring HPV and developing cervical cancer; examine the sociodemographic and behavioural factors associated with perceived risk; and assess HPV vaccine acceptability. Methods. AGYW aged 16 -24 years participating in the AYAZAZI study in Durban, South Africa (SA), were invited to participate in the AYA-HPV Prevention Project (AHPP), and were administered a questionnaire that assessed HPV, cervical cancer and vaccine awareness and knowledge, self-perceived HPV and cervical cancer risk, HPV vaccine uptake and acceptability, and participation in cervical cancer screening. The questionnaire measured self-perceived risk of acquiring HPV and developing cervical cancer for the respondent and other young women, as well as vaccine acceptability. Data from the main AYAZAZI study (12-month) visit were linked to AHPP substudy data. Descriptive statistics were used to analyse sociodemographic variables at the 12-month time point. Self-perceived HIV, HPV and cervical cancer risk was measured using an ordinal scale. Chi-square analyses were used to examine differences in sociodemographic and behavioural factors according to self -perceived risk of HPV and cervical cancer. Results. Only a small portion of participants (14.3%) had heard of HPV. Overall, 43.0% (n=49) perceived themselves as at low HPV risk. There were significant differences in self-perceived risk of cervical cancer by age group, income and pregnancy status. The highest proportion of AGYW who perceived themselves as at high risk of cervical cancer reported being sexually active (p=0.002). Although many participants reported not knowing about HPV prior to the study, after learning about it during the study, most said that they would be willing to receive the vaccine (97.5%). Conclusions. Most young women in SA do not have access to the national HPV vaccine programme, as only girls in grade 4 in some public schools qualify. Almost all participants indicated that if the vaccine was free and recommended by a healthcare professional, they would accept it. Availability of the HPV vaccine and timely treatment of HPV infections are key issues to address in efforts to decrease cervical cancer worldwide.

引用

页码：887 / 893

页数：7