Modified autologous matrix-induced chondrogenesis (AMIC) for the treatment of a large osteochondral defect in a varus knee: a case report

被引：8

作者：

de Girolamo, L. ^{[2
]}

Quaglia, A. ^{[1
]}

Bait, C. ^{[1
]}

Cervellin, M. ^{[1
]}

Prospero, E. ^{[1
]}

Volpi, P. ^{[1
]}

机构：

[1] IRCCS Ist Clin Humanitas, Knee Surg & Sport Traumatol Unit, Rozzano, MI, Italy

[2] IRCCS Galeazzi Orthopaed Inst, Orthopaed Biotechnol Lab, Milan, Italy

来源：

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY | 2012年 / 20卷 / 11期

关键词：

Osteochondral lesion; Autologous matrix-induced chondrogenesis; Varus knee; Osteotomy; Concentrated bone marrow; Bone graft; SUBCHONDRAL BONE; STEM-CELLS; REPAIR;

D O I：

10.1007/s00167-012-2143-y

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

This paper presents a case report of a 27-year-old male patient affected by a large osteochondral defect of the medial femoral condyle (6 cm(2)) in a varus knee. He was treated with a combined approach consisting of high tibial osteotomy and autologous matrix-induced chondrogenesis technique enhanced by a bone marrow-enriched bone graft. Twelve months after surgery, the patient reported considerable reduction in pain and significant increase in his quality of life. A hyaline-like cartilage completely covered the defect and was congruent with the surrounding condyle cartilage as revealed by MRI and by a second-look arthroscopy. Level of evidence IV.

引用

页码：2287 / 2290

页数：4

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