Novel Anticancer Agents and Targets: Recent Advances and Future Perspectives

被引：1

作者：

Barot, Kuldipsinh P. ^{[1
]}

Nikolova, Stoyanka ^{[2
]}

Ivanov, Illiyan ^{[2
]}

Ghate, Manjunath D. ^{[1
]}

机构：

[1] Nirma Univ, Inst Pharm, Dept Pharmaceut Chem, Ahmadabad 382481, Gujarat, India

[2] Paisij Hilendarski Univ Plovdiv, Fac Chem, Plovdiv 4000, Bulgaria

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2013年 / 13卷 / 09期

关键词：

Cancer; novel anticancer agents; novel heterocyclic compounds; novel anticancer targets; chemogenomics; FARNESYL TRANSFERASE INHIBITORS; IN-VITRO; TOPOISOMERASE-I; BREAST-CANCER; ANTITUMOR BENZOTHIAZOLES; BIOLOGICAL EVALUATION; DRUG DISCOVERY; ANTIESTROGENIC PROPERTIES; CYTOTOXICITY EVALUATION; AROMATASE INHIBITORS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An urgent need for the discovery of novel anticancer agents is required for the long term therapy of cancer. Large number of novel bio-active and potential anticancer agents are being used in clinical and pre-clinical trials. Although many heterocyclic compounds are already available commercially as anticancer agents, great efforts have been put to identify novel anticancer targets. This review provides an insight of the novel anticancer targets and molecules of the first and final stage of clinical and pre-clinical trials.

引用

页码：1239 / 1255

页数：17

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