Analysis of Inhomogeneous Static Magnetic Field-Induced Antinociceptive Activity in Mice

被引：0

作者：

Laszlo, Janos F. ^{[1
]}

Gyires, Klara ^{[2
]}

机构：

[1] Hungarian Acad Sci, Inst Res Org, Nador U 18, H-1051 Budapest, Hungary

[2] Semmelweis Univ, Dept Pharmacol & Pharmacotherapy, Budapest, Hungary

来源：

PIERS 2010 XI'AN: PROGRESS IN ELECTROMAGNETICS RESEARCH SYMPOSIUM PROCEEDINGS, VOLS 1 AND 2 | 2010年

关键词：

PAIN; ANALGESIA; BEHAVIOR; THERAPY;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The effect of inhomogeneous static magnetic field (SMF) on visceral pain elicited by the intraperitoneal injection of 0.6% acetic acid (writhing test) was studied in mice in an environment, where animals could freely move. 30 mm, whole-body exposure of mice to SMF (permanent NdFeB N50 grade 10 x 10 mm cylindrical magnets with alternating poles) following the nociceptive challenge resulted in a 74% inhibition of the pain reaction (p < 0.001). With the help of several inhomogeneous SMF configurations, where magnets were grouped in partitions and a 2D model of ambulation, motion-induced electric current density, MR-equivalent switching, and slew rate were estimated. Their potential contribution to peripheral nerve stimulation is discussed in correlation to pain inhibition.

引用

页码：1181 / +

页数：3

共 28 条

[1] Static magnetic fields for treatment of fibromyalgia: A randomized controlled trial [J].

Alfano, AP ;

Taylor, AG ;

Foresman, PA ;

Dunkl, PR ;

McConnell, GG ;

Conaway, MR ;

Gillies, GT .

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 2001, 7 (01) :53-64

[2] Exposure to Inhomogeneous Static Magnetic Field Ceases Mechanical Allodynia in Neuropathic Pain in Mice [J].

Antal, Miklos ;

Laszlo, Janos .

BIOELECTROMAGNETICS, 2009, 30 (06) :438-445

[3] Efficacy of static magnetic field therapy in chronic pelvic pain: A double-blind pilot study [J].

Brown, CS ;

Ling, FW ;

Wan, JY ;

Pilla, AA .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2002, 187 (06) :1581-1587

[4] Voluntary running in deer mice: speed, distance, energy costs and temperature effects [J].

Chappell, MA ;

Garland, T ;

Rezende, EL ;

Gomes, FR .

JOURNAL OF EXPERIMENTAL BIOLOGY, 2004, 207 (22) :3839-3854

[5] Effects of magnetic field exposure on open field behaviour and nociceptive responses in mice [J].

Del Seppia, C ;

Mezzasalma, L ;

Chloeris, E ;

Luschi, P ;

Ghione, S .

BEHAVIOURAL BRAIN RESEARCH, 2003, 144 (1-2) :1-9

[6] Biological effects of exposure to magnetic resonance imaging: an overview [J].

Formica, Domenico ;

Silvestri, Sergio .

BIOMEDICAL ENGINEERING ONLINE, 2004, 3 (1)

[7]

Guidelines on Exposure to Electromagnetic Fields from Magnetic Resonance Clinical Systems, 1987, 87EHD127 MIN NAT HLT

[8] Pharmacological analysis of inhomogeneous static magnetic field-induced antinociceptive action in the mouse [J].

Gyires, Klara ;

Zadori, Zoltan S. ;

Racz, Bernadette ;

Laszlo, Janos .

BIOELECTROMAGNETICS, 2008, 29 (06) :456-462

[9]

Hinman MR, 2002, ALTERN THER HEALTH M, V8, P50

[10]

Hofmann S., 1980, Surface and Interface Analysis, V2, P148, DOI 10.1002/sia.740020406

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