Endoscopic Management of Sinonasal Hemangiopericytoma

被引:24
作者
Tessema, Belachew [2 ]
Eloy, Jean Anderson [1 ,3 ]
Folbe, Adam J. [4 ]
Anstead, Amy S. [5 ]
Mirani, Neena M. [6 ]
Joudy, Deya N. [7 ]
Ruiz, Jose W. [7 ]
Casiano, Roy R. [7 ]
机构
[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Otolaryngol Head & Neck Surg, Newark, NJ 07103 USA
[2] Univ Connecticut, Connecticut Sinus Inst, Farmington, CT USA
[3] Univ Med & Dent New Jersey, New Jersey Med Sch, Neurol Inst New Jersey, Ctr Skull Base & Pituitary Surg, Newark, NJ 07103 USA
[4] Wayne State Univ, Dept Otolaryngol Head & Neck Surg, Detroit, MI USA
[5] Virginia Mason Med Ctr, Seattle, WA 98101 USA
[6] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Pathol, Newark, NJ 07103 USA
[7] Univ Miami, Leonard Miller Sch Med, Dept Otolaryngol Head & Neck Surg, Miami, FL USA
关键词
hemangiopericytoma; sinonasal tumors; epistaxis; sinonasal hemangiopericytoma; malignant sinonasal tumors; endoscopic sinus surgery; endoscopic skull base surgery; perivascular tumors; anterior skull base resection; ANTERIOR SKULL BASE; MALIGNANT-TUMORS; RESECTION; SINUS; SURGERY;
D O I
10.1177/0194599811427660
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective. Sinonasal hemangiopericytomas (SNHPCs) are rare perivascular tumors with low-grade malignant potential. Traditionally, these tumors have been treated with open approaches such as lateral rhinotomy, Caldwell-Luc, or transfacial approaches. Increased experience with endoscopic management of benign and malignant sinonasal tumors has led to a shift in management of SNHPC. The authors present their experience in the largest series of patients with SNHPC managed endoscopically. Study Design and Setting. Case series at a tertiary care medical center. Subjects and Method. A retrospective chart review of all patients undergoing endoscopic management of SNHPC at the University of Miami between 1999 and 2008 was conducted. All endoscopic resections were performed with curative intent. Results. Twelve patients with the diagnosis of SNHPC were treated endoscopically. Mean age was 62.5 years (range, 51-83 years). There were 6 men and 6 women. The mean follow-up was 41 months (range, 15-91 months). Seven (58.3%) presented with nasal obstruction, whereas 4 (41.6%) had epistaxis as their initial presenting symptom. Preoperative angiography or embolization was not performed in any case. Mean estimated blood loss was 630 mL (range, 100-1500 mL). Six patients underwent endonasal endoscopic anterior skull base resection; 4 had complete endoscopic resection all with negative margins. None underwent postoperative adjuvant treatment. No recurrence or metastatic disease was observed in this patient population. Conclusion. Endoscopic management of SNHPC is a feasible approach and did not compromise outcomes in this experience. In this series, familiarity with advance endoscopic sinus surgery was necessary to manage these patients. Postoperative adjuvant therapy was not necessary in this cohort.
引用
收藏
页码:483 / 486
页数:4
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