SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME NEW BENZO (b) THIOPHENE DERIVATIVES

被引:0
作者
Tirlapur, Vijaykumar [1 ]
Khan, Younus [1 ]
Waseemuddin, Syed [1 ]
机构
[1] Karnataka Coll Pharm, Dept Pharmaceut Chem, Bidar 585403, India
关键词
INHIBITORS; SERIES;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pyrazoles, oxadiazoles and triazoles bearing benzo[b] thiophene moiety have been prepared starting from 3-chloro-6-methoxy-1-benzothiophen-2-carbonyl chloride. All the newly synthesized compounds were characterized by elemental analysis, IR, H-1 NMR and mass spectral studies and screened for their antibacterial and antifungal activities.
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页码:383 / 388
页数:6
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共 7 条
  • [1] [Anonymous], 1996, INDIAN PHARMACOPOEIA, P11
  • [2] Synthesis and evaluation of new arylbenzo[b]thiophene and diarylthiophene derivatives as inhibitors of the NorA multidrug transporter of Staphylococcus aureus
    Chabert, Jeremie Fournier dit
    Marquez, Beatrice
    Neville, Luc
    Joucla, Lionel
    Broussous, Sylvie
    Bouhours, Pascale
    David, Emilie
    Pellet-Rostaing, Stephane
    Marquet, Bernard
    Moreau, Nicole
    Lemaire, Marc
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (13) : 4482 - 4497
  • [3] Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
    Ferreira, ICFR
    Queiroz, MJRP
    Vilas-Boas, M
    Estevinho, LM
    Begouin, A
    Kirsch, G
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (05) : 1384 - 1387
  • [4] New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: Synthesis, resolution, and inhibitory activity
    Krajewski, K
    Zhang, YJ
    Parrish, D
    Deschamps, J
    Roller, PP
    Pathak, VK
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (11) : 3034 - 3038
  • [5] Synthesis and antimicrobial activity studies of ortho-chlorodiarylamines and heteroaromatic tetracyclic systems in the benzo[b]thiophene series
    Queiroz, Maria-Joao R. P.
    Ferreira, Isabel C. F. R.
    De Gaetano, Yannick
    Kirsch, Gilbert
    Calhelha, Ricardo C.
    Estevinho, Leticia M.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (20) : 6827 - 6831
  • [6] Tirlapur VK, 2010, INDIAN J HETEROCY CH, V20, P141
  • [7] Synthesis and cytotoxic activity of lipophilic sulphonamide derivatives of the benzo[b]thiophene 1,1-dioxide
    Villar, R
    Encio, I
    Migliaccio, M
    Gil, MJ
    Martinez-Merino, V
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (05) : 963 - 968