Ependymal cells in the spinal cord as neuronal progenitors

被引：22

作者：

Moreno-Manzano, Victoria ^{[1
]}

机构：

[1] Ctr Invest Principe Felipe, Neuronal & Tissue Regenerat Lab, Valencia, Spain

来源：

CURRENT OPINION IN PHARMACOLOGY | 2020年 / 50卷

关键词：

NEURAL STEM-CELLS; STEM/PROGENITOR CELLS; GLIAL-CELLS; PHASE-I; INJURY; TRANSPLANTATION; ORIGIN; DIFFERENTIATION; NEUROGENESIS; EXPRESSION;

D O I：

10.1016/j.coph.2019.11.008

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Ependymal cells are neural progenitors and form part of the central canal of the spinal cord. Therefore, ependymal cells could serve as a potential source of neural progenitors for regenerative medicine applications. Such applications consist of endogenous activation or exogenous transplantation, alone or in combination with pharmacological treatments, to repair spinal cord injuries. This mini review describes the main phenotypical characteristics of ependymal cells from spinal cord and the opportunities offered for spinal cord injury therapeutic application.

引用

页码：82 / 87

页数：6

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