Oxygen-induced hypercapnia in COPD: myths and facts

被引：95

作者：

Abdo, Wilson F. ^{[1
]}

Heunks, Leo M. A. ^{[1
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Intens Care Med, NL-6500 HB Nijmegen, Netherlands

来源：

CRITICAL CARE | 2012年 / 16卷 / 05期

关键词：

OBSTRUCTIVE PULMONARY-DISEASE; ACUTE EXACERBATIONS; VENTILATION;

D O I：

10.1186/cc11475

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

During our medical training, we learned that oxygen administration in patients with chronic obstructive pulmonary disease (COPD) induces hypercapnia through the 'hypoxic drive' mechanism and can be dangerous. This mindset frequently results in the reluctance of clinicians to administer oxygen to hypoxemic patients with COPD. However, this fear is not based on evidence in the literature. Here, we will review the impact and pathophysiology of oxygen-induced hypercapnia in patients with acute exacerbation of COPD and recommend a titrated oxygen management.

引用

页数：4

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