Outcomes After Surgical Pulmonary Embolectomy for Acute Pulmonary Embolus: A Multi-Institutional Study

被引:79
作者
Keeling, W. Brent
Sundt, Thor
Leacche, Marzia
Okita, Yutaka
Binongo, Jose
Lasajanak, Yi
Aklog, Lishan
Lattouf, Omar M.
机构
[1] Emory Univ, Div Cardiothorac Surg, Atlanta, GA 30322 USA
[2] Massachusetts Gen Hosp, Div Cardiothorac Surg, Boston, MA 02114 USA
[3] Brigham & Womens Hosp, Div Cardiothorac Surg, 75 Francis St, Boston, MA 02115 USA
[4] Kobe Univ, Div Cardiothorac Surg, Kobe, Hyogo, Japan
[5] Pavil Holdings Grp, New York, NY USA
关键词
EXTRACORPOREAL MEMBRANE-OXYGENATION; DEEP-VEIN THROMBOSIS; MANAGEMENT;
D O I
10.1016/j.athoracsur.2016.05.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. Surgical pulmonary embolectomy (SPE) has been sparingly used for the successful treatment of massive and submassive pulmonary emboli. To date, all data regarding SPE have been limited to single-center experiences. The purpose of this study was to document short-term outcomes after SPE for acute pulmonary emboli (PE) at four high-volume institutions. Methods. A retrospective review of multiple local Society of Thoracic Surgeons databases of adults undergoing SPE from 1998 to 2014 for acute PE was performed (n = 214). Demographic, operative, and outcomes data were collected and analyzed. Patients were summarily categorized as having either massive or submassive PEs based on the presence or absence of preoperative vasopressors. Results. A total of 214 patients with acute PE were treated by SPE. The mean age was 56.0 +/- 14.5 years, and 92 (43.6%) patients were female. Of those, 176 (82.2%) PEs were submassive and 38 (17.8%) were massive. Fifteen (7.0%) patients underwent concomitant cardiac procedures, with 10 (4.7%) having simultaneous valvular interventions and 5 (2.4%) undergoing concomitant bypass grafting. Cardiopulmonary bypass (CPB) was used for all cases. Cardioplegic arrest was used for 80 (37.4%) patients. The median CPB and aortic cross clamp times were 71.5 (interquartile range [IQR], 47.0-109.5) and 46.0 (IQR, 26.0-74.5), respectively. Notably, only 25 (11.7%) patients died in the hospital. Mortality was highest among the 28 patients who experienced preoperative cardiac arrest (9, 32.1%) Conclusions. These data represent the first multicenter experience with SPE for acute pulmonary emboli. Surgical pulmonary embolectomy for acute massive and submassive PE is safe and can be performed with acceptable in-hospital outcomes; the procedure should be included in the multimodality treatment of life-threatening pulmonary emboli. (C) 2016 by The Society of Thoracic Surgeons
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页码:1498 / 1502
页数:5
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