Peripheral Mechanisms in Irritable Bowel Syndrome

被引:226
作者
Camilleri, Michael [1 ]
机构
[1] Mayo Clin, Coll Med, Rochester, MN 55905 USA
关键词
FUNCTIONAL GASTROINTESTINAL DISORDERS; BILE-ACID MALABSORPTION; CHAIN FATTY-ACIDS; GLUTEN-FREE DIET; CELIAC-DISEASE; COLONIC TRANSIT; CHROMOGRANIN-A; MACROMOLECULAR PERMEABILITY; VISCERAL HYPERSENSITIVITY; ENTEROENDOCRINE CELLS;
D O I
10.1056/NEJMra1207068
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1626 / 1635
页数:10
相关论文
共 101 条
[1]   Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome [J].
Aerssens, Jeroen ;
Camilleri, Michael ;
Talloen, Willem ;
Thielemans, Leen ;
Goehlmann, Hinrich W. H. ;
Van den Wyngaert, Ilse ;
Thielemans, Theo ;
De Hoogt, Ronald ;
Andrews, Christopher N. ;
Bharucha, Adil E. ;
Carlson, Paula J. ;
Busciglio, Irene ;
Burton, Duane D. ;
Smyrk, Thomas ;
Urrutia, Raul ;
Coulie, Bernard .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2008, 6 (02) :194-205
[2]   Acute experimental stress evokes a differential gender-determined increase in human intestinal macromolecular permeability [J].
Alonso, C. ;
Guilarte, M. ;
Vicario, M. ;
Ramos, L. ;
Rezzi, S. ;
Martinez, C. ;
Lobo, B. ;
Martin, F. -P. ;
Pigrau, M. ;
Gonzalez-Castro, A. M. ;
Gallart, M. ;
Malagelada, J. R. ;
Azpiroz, F. ;
Kochhar, S. ;
Santos, J. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2012, 24 (08) :740-+
[3]   The proximal colonic motor response to rectal mechanical and chemical stimulation [J].
Bampton, PA ;
Dinning, PG ;
Kennedy, ML ;
Lubowski, DZ ;
Cook, IJ .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2002, 282 (03) :G443-G449
[4]   Mechanisms underlying visceral hypersensitivity in irritable bowel syndrome [J].
Barbara G. ;
Cremon C. ;
De Giorgio R. ;
Dothel G. ;
Zecchi L. ;
Bellacosa L. ;
Carini G. ;
Stanghellini V. ;
Corinaldesi R. .
Current Gastroenterology Reports, 2011, 13 (4) :308-315
[5]   Gluten Causes Gastrointestinal Symptoms in Subjects Without Celiac Disease: A Double-Blind Randomized Placebo-Controlled Trial [J].
Biesiekierski, Jessica R. ;
Newnham, Evan D. ;
Irving, Peter M. ;
Barrett, Jacqueline S. ;
Haines, Melissa ;
Doecke, James D. ;
Shepherd, Susan J. ;
Muir, Jane G. ;
Gibson, Peter R. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2011, 106 (03) :508-514
[6]  
Bouchoucha M, 2009, TECH COLOPROCTOL, V13, P103
[7]  
Camilleri M, 2012, NEUROGASTROENT MOTIL, V24, P23
[8]   Pharmacology of the New Treatments for Lower Gastrointestinal Motility Disorders and Irritable Bowel Syndrome [J].
Camilleri, M. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2012, 91 (01) :44-59
[9]   Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis [J].
Camilleri, M. ;
Carlson, P. ;
McKinzie, S. ;
Zucchelli, M. ;
D'Amato, M. ;
Busciglio, I. ;
Burton, D. ;
Zinsmeister, A. R. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2011, 23 (10) :935-E398
[10]   Measurement of serum 7α-hydroxy-4-cholesten-3-one (or 7αC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry [J].
Camilleri, M. ;
Nadeau, A. ;
Tremaine, W. J. ;
Lamsam, J. ;
Burton, D. ;
Odunsi, S. ;
Sweetser, S. ;
Singh, R. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2009, 21 (07) :734-E43