Clinical Observation of Fetal Olfactory Ensheathing Glia Transplantation (OEGT) in Patients With Complete Chronic Spinal Cord Injury

被引：44

作者：

Wu, Jun ^{[1
]}

Sun, Tiansheng ^{[1
]}

Ye, Chaoqun ^{[1
]}

Yao, Jianhua ^{[1
]}

Zhu, Bing ^{[1
]}

He, Hongying ^{[1
]}

机构：

[1] Beijing Army Gen Hosp, Dept Orthoped, Beijing 100700, Peoples R China

来源：

CELL TRANSPLANTATION | 2012年 / 21卷

关键词：

Spinal cord injury (SCI); Olfactory ensheathing cells; Cell transplantation; Clinical observation; CELL TRANSPLANTATION; FUNCTIONAL RECOVERY; ICCP PANEL; REGENERATION; GUIDELINES; CONDUCT; TRIALS;

D O I：

10.3727/096368912X633743

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

This study was designed to observe the functional changes after fetal olfactory ensheathing glia transplantation (OEGT) into the spinal cord of patients with chronic spinal cord injury (SCI). Patients whose recovery had plateaued for longer than 6 months were enrolled. Six thoracic patients were tested for safety and five cervical patients for efficacy. OEGT was performed according to the method developed by Huang. Average follow-up was 14 months (range 1.0-1.5 years). Sensation improved moderately (light touch 14.2, pin prick 13.6); as did spasticity (1-2 modified Ashworth scale down). Locomotion recovery was minimal (1.6). Useful reticular formation functions were observed, but due to a lack of appropriate outcome measure, they were not recorded and reported.

引用

页码：S33 / S37

页数：5

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