Medication errors detected in elderly patients admitted to an internal medicine service

被引:9
作者
Garcia-Aparicio, J. [1 ]
Herrero-Herrero, J. I. [1 ]
机构
[1] Univ Hosp, Internal Med Serv Los Montalvos, Salamanca 37192, Spain
关键词
ADVERSE DRUG EVENTS; PREVALENCE; DISCREPANCIES; ADMISSIONS; CARE; HOSPITALS;
D O I
10.1111/j.1742-1241.2012.02982.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: The aim of the work was to analyse the outpatient medication errors detected on admission in senior patients in a Spanish general internal medicine service. Patients and methods: We carried out a retrospective cohort study based on a review of the admission reports of consecutive, non-selected, patients aged 65years. Results: Eight hundred and sixty admission reports (cases) were analysed. Overall, we detected 218 errors in 173 (20.1%) of them. Wrong drug' errors were found in 165 occasions (75.7% of the 218 detected errors), being the most frequent among these not indicated/inappropriate drug for the diagnosis' (61 cases, 28.0%), followed by not indicated/inappropriate drug for the patient's condition' (55 cases, 25.2%). The binary logistic regression analysis showed association (p<0.05) between medication errors and sex (female) (OR 0.53, 95%, CI 0.370.76), cognitive impairment (OR 0.57, 95% CI 0.380.85), length of hospital stay (OR 1.06, 95% CI 1.001.11), number of diagnoses (OR 0.92, 95% CI 0.850.98), number of medicines at admission (OR 1.20, 95% CI 1.131.28) and lack of a recent previous admission in an internal medicine department (OR 2.07, 95% CI 1.143.74). Conclusion: Although previous studies are not completely comparable, the incidence of errors found at admission in our study is low. We stress the relevance of the reconciliation of treatment in elderly people (where internists may play an important role, from their perspective of a comprehensive patient's care) and integrated procedures for medication prescription and dispensation.
引用
收藏
页码:282 / 289
页数:8
相关论文
共 43 条
[1]  
Altman DG, 1990, PRACTICAL STAT MED R, DOI DOI 10.1201/9780429258589
[2]   Medication use leading to emergency department visits for adverse drug events in older adults [J].
Budnitz, Daniel S. ;
Shehab, Nadine ;
Kegler, Scott R. ;
Richards, Chesley L. .
ANNALS OF INTERNAL MEDICINE, 2007, 147 (11) :755-U26
[3]   Adverse drug events in hospitalized elderly in a Geriatric medicine unit: Study of prevalence and risk factors [J].
Cecile, M. ;
Seux, V. ;
Pauly, V. ;
Tassy, S. ;
Reynaud-Levy, O. ;
Dalco, O. ;
Thirion, X. ;
Soubeyrand, J. ;
Retornaz, F. .
REVUE DE MEDECINE INTERNE, 2009, 30 (05) :393-400
[4]   Unintended medication discrepancies at the time of hospital admission [J].
Cornish, PL ;
Knowles, SR ;
Marchesano, R ;
Tam, V ;
Shadowitz, S ;
Juurlink, DN ;
Etchells, EE .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (04) :424-429
[5]   A prevalence study of errors in opioid prescribing in a large teaching hospital [J].
Davies, E. Denison ;
Schneider, F. ;
Childs, S. ;
Hucker, T. ;
Krikos, D. ;
Peh, J. ;
McGowan, C. ;
Stone, P. ;
Cashman, J. .
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2011, 65 (09) :923-929
[6]   Potentially inappropriate among elderly home medication use care patients in Europe [J].
Fialová, D ;
Topinková, E ;
Gambassi, G ;
Finne-Soveri, H ;
Jónsson, PV ;
Carpenter, I ;
Schroll, M ;
Onder, G ;
Sorbye, LW ;
Wagner, C ;
Reissigová, J ;
Bernabei, R .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 293 (11) :1348-1358
[7]   Updating the beers criteria for potentially inappropriate medication use in older adults - Results of a US consensus panel of experts [J].
Fick, DM ;
Cooper, JW ;
Wade, WE ;
Waller, JL ;
Maclean, JR ;
Beers, MH .
ARCHIVES OF INTERNAL MEDICINE, 2003, 163 (22) :2716-2724
[8]   Prevalence, clinical features and avoidability of adverse drug reactions as cause of admission to a Geriatric Unit - A prospective study of 1756 patients [J].
Franceschi, Marilisa ;
Scarcelli, Carlo ;
Niro, Valeria ;
Seripa, Davide ;
Pazienza, Anna Maria ;
Pepe, Giovanni ;
Colusso, Anna Maria ;
Pacilli, Luigi ;
Pilotto, Alberto .
DRUG SAFETY, 2008, 31 (06) :545-556
[9]   The Nordic Countries as a Cohort for Pharmacoepidemiological Research [J].
Furu, Kari ;
Wettermark, Bjorn ;
Andersen, Morten ;
Martikainen, Jaana E. ;
Almarsdottir, Anna Birna ;
Sorensen, Henrik Toft .
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2010, 106 (02) :86-94
[10]   Reconciliation of discrepancies in medication histories and admission orders of newly hospitalized patients [J].
Gleason, KM ;
Groszek, JM ;
Sullivan, C ;
Rooney, D ;
Barnard, C ;
Noskin, GA .
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2004, 61 (16) :1689-1695