Novel coumarin-based containing denrons selective fluorescent chemosesor for sequential recognition of Cu2+ and PPi

被引：26

作者：

Zhao, Chongyang ^{[1
]}

Chen, Jian ^{[1
]}

Cao, Duanlin ^{[1
]}

Wang, Jianlong ^{[1
]}

Ma, Wenbing ^{[1
]}

机构：

[1] North Univ China, Sch Chem Engn & Technol, Taiyuan 030051, Shanxi, Peoples R China

来源：

TETRAHEDRON | 2019年 / 75卷 / 13期

关键词：

Fluorescent probe; Coumarin; Dendrons; Cu2+; PPi; On-off-on sensor; ON-OFF-ON; SENSITIVE DETECTION; LIVE CELLS; PROBE; COPPER; SENSOR; IONS; DESIGN; PYROPHOSPHATE; DENDRONS;

D O I：

10.1016/j.tet.2019.02.024

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this study, we have successfully synthesized a novel coumarin-based dendrons derivative CD and its chemical structure was characterized by H-1 NMR, C-13 NMR and ESI-HR-MS. The sensor CD showed an obvious "on-off' fluorescence quenching response toward Cu2+ with a maximum quenching efficiency of 99.8%. The CD-Cu2+ complex showed an "off-on" fluorescence enhancement response toward PPi over many competitive anions. The detection limit of the sensor CD was 0.29 x 10(-6) M to Cu2+ and 239 x 10-9M to PPi. In addition, the sensor CD showed a 1:1 binding stoichiometry to Cu2+ and the sensor CD-Cu2+ showed a 2:1 binding stoichiometry to PPi in CH3CN/HEPES buffer medium (9:1 v/v, pH = 7.2). The stable pH range of sensor CD to Cu2+ and CD-Cu2+ to PPi was from 3 to 8. (C) 2019 Elsevier Ltd. All rights reserved.

引用

页码：1997 / 2003

页数：7

共 48 条

[1] Metal transporters and disease [J].

Andrews, NC .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (02) :181-186

[2] A multi-ion fluorescent probe for Mg2+/Zn2+ based on a novel chromone-dendron Schiff base [J].

Bai, Xue ;

Yan, Jun ;

Qin, Jing-can ;

Yang, Zheng-yin .

INORGANICA CHIMICA ACTA, 2018, 474 :44-50

[3] Near-infrared fluorescent probe for sensitive detection of Pb(II) ions in living cells [J].

Bi, Jianheng ;

Fang, Mingxi ;

Wang, Jianbo ;

Xia, Shuai ;

Zhang, Yibin ;

Zhang, Jingtuo ;

Vegesna, Giri ;

Zhang, Shuwei ;

Tanasova, Marina ;

Luo, Fen-Tair ;

Liu, Haiying .

INORGANICA CHIMICA ACTA, 2017, 468 :140-145

[4] Design and Synthesis of New Cationic Water-Soluble Pyrene Containing Dendrons for DNA Sensory Applications [J].

Chen, Ching-Yi ;

Ito, Yumiko ;

Chiu, Yu-Cheng ;

Wu, Wen-Chung ;

Higashihara, Tomoya ;

Ueda, Mitsuru ;

Chen, Wen-Chang .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2012, 50 (02) :297-305

[5] A coumarin-based colorimetric and fluorescent dual probe for palladium(II) ions that can be used in live cells [J].

Chen, Xiang-Zhu ;

Ma, Xiao-Dong ;

Wang, Hong-Mei ;

Wang, Mian ;

Zhang, Yuan-Yuan ;

Gao, Gui ;

Liu, Jing-Jing ;

Hou, Shi-Cong .

NEW JOURNAL OF CHEMISTRY, 2017, 41 (16) :8026-8030

[6] Proton-conductive materials formed by coumarin photocrosslinked ionic liquid crystal dendrimers [J].

Concellon, Alberto ;

Liang, Ting ;

Schenning, Albertus P. H. J. ;

Luis Serrano, Jose ;

Romero, Pilar ;

Marcos, Mercedes .

JOURNAL OF MATERIALS CHEMISTRY C, 2018, 6 (05) :1000-1007

[7] Novel PAMAM Dendron as a Bichromophoric Probe Based on Rhodamine 6G and 1,8-Naphthalimide [J].

Dimitrova, Margarita D. ;

Georgiev, Nikolai I. ;

Bojinov, Vladimir B. .

JOURNAL OF FLUORESCENCE, 2016, 26 (03) :1091-1100

[8] Novel reversible fluorescent probe for relay recognition of Zn2+ and PPi in aqueous medium and living cells [J].

Dong, Zhen Ming ;

Wang, Wei ;

Qin, Li Yuan ;

Feng, Jia ;

Wang, Jia Na ;

Wang, Yu .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2017, 335 :1-9

[9] Synthesis of Two Coumarin-Derived Schiff Bases and Investigation of theirs Selectivity for Zn2+ [J].

Fan, Long .

JOURNAL OF FLUORESCENCE, 2017, 27 (04) :1331-1337

[10]

Fang MX, 2017, J MATER CHEM B, V5, P9579, DOI [10.1039/C7TB02583A, 10.1039/c7tb02583a]

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