Enhancing the locality of optical interrogation with photonic-crystal fibers

被引:9
作者
Doronina-Amitonova, Lyubov V. [1 ,2 ]
Fedotov, Il'ya V. [1 ]
Ivashkina, Olga I. [2 ,3 ]
Zots, Marina A. [2 ,3 ]
Fedotov, Andrei B. [1 ,2 ]
Anokhin, Konstantin V. [2 ,3 ]
Zheltikov, Aleksei M. [1 ,2 ,4 ]
机构
[1] Moscow MV Lomonosov State Univ, Ctr Int Laser, Russian Quantum Ctr, Dept Phys, Moscow 117234, Russia
[2] Kurchatov Natl Res Ctr, Dept Neurosci, Moscow, Russia
[3] Russian Acad Med Sci, PK Anokhin Inst Normal Physiol, Moscow, Russia
[4] Texas A&M Univ, Dept Phys & Astron, College Stn, TX 77843 USA
基金
俄罗斯基础研究基金会;
关键词
SUPERCONTINUUM GENERATION; FLUORESCENCE MICROSCOPY; SOLITON OUTPUT; PULSES; LIGHT; RAMAN;
D O I
10.1063/1.4727901
中图分类号
O59 [应用物理学];
学科分类号
摘要
Small-core photonic-crystal fibers (PCFs) are shown to enhance the locality of optical interrogation in fiber-probe-based imaging. We demonstrate that, in a typical fluorescence imaging experiment, the longitudinal dimension of the interrogated region closely follows the a(m) tan(-1) theta(d) scaling with the effective mode radius a(m) and the beam-divergence angle theta(d). The confinement of optical interrogation provided by small-core, high-index-step PCF probes is high enough to enable interrogation of individual neurons in a typical brain imaging experiment. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4727901]
引用
收藏
页数:4
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