Reprint of "Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR"

被引:4
作者
Okello, Anna L. [1 ,2 ,3 ]
Thomas, Lian
Inthavong, Phouth [4 ]
Ash, Amanda [5 ]
Khamlome, Boualam [6 ]
Keokamphet, Chattouphone [4 ]
Newberry, Kim [1 ]
Gauci, Charles G. [7 ]
Gabriel, Sarah [8 ]
Dorny, Pierre [8 ]
Thompson, R. C. Andrew [5 ]
Lightowlers, Marshall W. [7 ]
Allen, John [1 ]
机构
[1] CSIRO, Australian Anim Hlth Lab AAHL Reg Programme, Geelong, Vic, Australia
[2] Univ Edinburgh, Div Pathway Med, Sch Biomed Sci, Coll Med & Vet Med, Chancellors Bldg,49 Little France Crescent, Edinburgh EH16 4SB, Midlothian, Scotland
[3] Univ Edinburgh, Ctr Infect Dis, Sch Biomed Sci, Coll Med & Vet Med, Chancellors Bldg,49 Little France Crescent, Edinburgh EH16 4SB, Midlothian, Scotland
[4] Minist Agr, Natl Anim Hlth Lab, Dept Livestock & Fisheries, Viangchan, Laos
[5] Murdoch Univ, Sch Vet & Life Sci, Perth, WA, Australia
[6] Minist Hlth, Dept Hyg & Prevent, Vientiane Capital, Laos
[7] Univ Melbourne, Fac Vet & Agr Sci, 250 Princes Highway, Werribee, Vic 3030, Australia
[8] Inst Trop Med, Dept Biomed Sci, Natl Str 155, B-2000 Antwerp, Belgium
基金
英国医学研究理事会;
关键词
SOUTHEAST-ASIA; CYSTICERCOSIS; PREVALENCE; ZOONOSES; PEOPLE; HEALTH; FOCUS; PCR;
D O I
10.1016/j.actatropica.2016.11.010
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400 mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30 mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention. (C) 2016 The Author(s). Published by Elsevier B.V.
引用
收藏
页码:261 / 267
页数:7
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