Orthogonal Adsorption Onto Nano-Graphene Oxide Using Different Intermolecular Forces for Multiplexed Delivery

被引：45
作者：
Wang, Feng [1 ,2 ]
Liu, Biwu [1 ,2 ]
Ip, Alexander C-F [1 ,2 ]
Liu, Juewen [1 ,2 ]
机构：
[1] Univ Waterloo, Dept Chem, Waterloo, ON N2L 3G1, Canada
[2] Univ Waterloo, Waterloo Inst Nanotechnol, Waterloo, ON N2L 3G1, Canada
来源：
ADVANCED MATERIALS | 2013年 / 25卷 / 30期
基金：
加拿大自然科学与工程研究理事会;
关键词：
graphene oxide; liposomes; drug delivery; adsorption; GOLD NANOPARTICLES; DRUG-DELIVERY; PLATFORM; FUNCTIONALIZATION; CONJUGATE; BIOLOGY; HYBRID;
D O I：
10.1002/adma.201301183
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Nano-graphene oxide can adsorb both doxorubicin and zwitterionic dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes in an orthogonal and non-competing manner with high capacities based on different surface and intermolecular forces taking place on the heterogeneous surface of the graphene oxide. The system forms stable colloids, allowing co-delivery of both cargos to cancer cells. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：4087 / 4092
页数：6
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