Conjugation of 1-Aminoadamantanes and 5-Trifluoromethylhydantoins by 1,3-Dipolar Cycloaddition

被引：0
作者：
Sokolov, V. B. [1 ]
Aksinenko, A. Yu. [1 ]
Goreva, T. V. [1 ]
Epishina, T. A. [1 ]
Shestov, V. I. [1 ]
机构：
[1] Russian Acad Sci, Inst Physiol Act Cpds, Moscow 142432, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2020年 / 90卷 / 10期
关键词：
1-aminoadamantanes; 5-trifluoromethylhydantoins; methyl trifluoropyruvate imines; 1; 4-substituted; 2; 3-triazoles; 3-dipolar cycloaddition; MEDICINAL CHEMISTRY; METHYL TRIFLUOROPYRUVATE; CYCLOCONDENSATION; AMINOADAMANTANES; AGENTS;
D O I：
10.1134/S1070363220100035
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A synthetic approach was proposed for combining pharmacophore scaffolds, namely, 1-aminoadamantanes and 5-trifluoromethylhydantoins by the copper-catalyzed 1,3-dipolar alkyne-azide cycloaddition reaction.
引用
收藏
页码：1831 / 1835
页数：5
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