An allosteric site mutant of Ras stabilizes a catalytically active conformation of switch II

被引：0

作者：

Fetics, Susan Kathleen ^{[1
]}

Davis, Kathleen ^{[1
]}

Buhrman, Greg ^{[1
]}

Mattos, Carla ^{[1
]}

机构：

[1] N Carolina State Univ, Raleigh, NC 27695 USA

来源：

FASEB JOURNAL | 2011年 / 25卷

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页数：1

共 44 条

[21] Catalytically Competent Non-transforming H-RASG12P Mutant Provides Insight into Molecular Switch Function and GAP-independent GTPase Activity of RAS
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[22] Intriguing conformation changes associated with the trans/cis isomerization of a prolyl residue in the active site of the DsbA C33A mutant
不详
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2005, 34 (06): : 663 - 663
[23] Intriguing conformation changes associated with the trans/cis isomerization of a prolyl residue in the active site of the DsbA C33A mutant
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[24] The allosteric activator ATP induces a substrate-dependent alteration of the quaternary structure of a mutant aspartate transcarbamoylase impaired in active site closure
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[25] Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA
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[26] Switch-1 instability at the active site decouples ATP hydrolysis from force generation in myosin II
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[27] Roles of RNA:DNA hybrid stability, RNA structure, and active site conformation in pausing by human RNA polymerase II
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[28] Role of Allosteric Switch Residue Histidine 195 in Maintaining Active-Site Asymmetry in Presynaptic Filaments of Bacteriophage T4 UvsX Recombinase
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[29] RECOMBINANT CALPAIN-II - IMPROVED EXPRESSION SYSTEMS AND PRODUCTION OF A 105A ACTIVE-SITE MUTANT FOR CRYSTALLOGRAPHY
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[30] Crystal Structures of Trehalose Synthase from Deinococcus Radiodurans Reveal a Closed Conformation for Intramolecular Isomerization Catalysis and Mutant Induction of an Active-Site Aperture
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