Surface modification and biocompatible improvement of polystyrene film by Ar, O2 and Ar + O2 plasma

被引：44

作者：

Chen, Yashao ^{[1
]}

Gao, Qiang ^{[1
]}

Wan, Haiyan ^{[1
]}

Yi, Jinhong ^{[1
]}

Wei, Yanlin ^{[1
]}

Liu, Peng ^{[2
]}

机构：

[1] Shaanxi Normal Univ, Minist Educ, Sch Chem & Chem Engn, Key Lab Appl Surface & Colloid Chem, Xian 710062, Peoples R China

[2] Chongqing Univ, Minist Educ, Coll Bioengn, Key Lab Biorheol Sci & Technol, Chongqing 400044, Peoples R China

来源：

APPLIED SURFACE SCIENCE | 2013年 / 265卷

基金：

中国国家自然科学基金;

关键词：

Surface modification; Plasma treatment; PS; NVP; Biocompatibility;

D O I：

10.1016/j.apsusc.2012.11.027

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This paper reports the surface modification of different discharge gases (Ar, O-2, and Ar + O-2) plasma-treated polystyrene (PS) film by Ar plasma induced graft polymerization, with biocompatible monomer N-vinyl-2-pyrrolidone (NVP) is carried out to improve biocompatibility. The films are characterized by attenuated total reflectance Fourier transfer infrared (ATR-FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). Water contact angle measurement demonstrates the modified films possess a relatively hydrophilic surface. Furthermore, the films are also examined cell attachment and proliferation in vitro using mouse fibroblasts (L929 cells). The modified film surface shows a better cell distribution and growth than that of the pristine PS surface. From cell culture experiments, it is also observed that Ar + O-2 plasma is more capable of increasing cell adhesion and proliferation. This method will provide a potential and effective solution for grafting useful component in future tissue-engineering applications. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：452 / 457

页数：6

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