Targeting B7-H3 (CD276) in neuroblastoma: In vitro evaluation of Fc-optimized antibodies and immunocytokines

被引:2
|
作者
Heubach, Florian
Schlegel, Patrick
Zekri, Latifa
Manz, Timo
Schleicher, Sabine
Rabsteyn, Armin
Jung, Gundram
Buehring, Hans-Joerg
Gillies, Stephen D.
Handgretinger, Rupert
Lang, Peter
机构
[1] Childrens Univ Hosp, Tubingen, Germany
[2] Eberhard Karls Univ Tubingen, Tubingen, Germany
[3] German Canc Consortium DKTK, Tubingen, Germany
[4] German Canc Res Ctr, Tubingen, Germany
[5] Provenance Biopharmaceut, Carlisle, MA USA
关键词
D O I
10.1158/2326-6074.CRICIMTEATIAACR18-A131
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A131
引用
收藏
页数:2
相关论文
共 50 条
  • [21] CD276 (B7-H3) Is an Immunotherapeutic Target in Acute Myeloid Leukemia with Preclinical Efficacy of Vobramitamab Duocarmazine, an Investigational CD276 Antibody-Drug Conjugate
    Kirkey, Danielle C.
    Blankenfeld, Melia
    Hylkema, Tiffany
    Loo, Deryk
    Ward, Ashley
    Robinson, Leila
    Peplinski, Jack H.
    Wallace, Logan K.
    Pardo, Laura
    Menssen, Andrew J.
    Ries, Rhonda E.
    Meshinchi, Soheil
    BLOOD, 2023, 142
  • [22] Hopes on immunotherapy targeting B7-H3 in neuroblastoma
    Pulido, Rafael
    Nunes-Xavier, Caroline E.
    TRANSLATIONAL ONCOLOGY, 2023, 27
  • [23] Genetic and clinical characterization of B7-H3 (CD276) expression and epigenetic regulation in diffuse brain glioma
    Wang, Zhiliang
    Wang, Zheng
    Zhang, Chuanbao
    Liu, Xing
    Li, Guanzhang
    Liu, Shuai
    Sun, Lihua
    Liang, Jingshan
    Hu, Huimin
    Liu, Yanwei
    Zhang, Wei
    Jiang, Tao
    CANCER SCIENCE, 2018, 109 (09) : 2697 - 2705
  • [24] Pan-cancer associations of B7-H3 (CD276) transcriptional expression across human malignancies
    Hwang, Justin
    Zorko, Nick
    Elliott, Andrew
    Lozada, Jose A.
    Radovich, Milan
    Heath, Elisabeth I.
    Agarwal, Neeraj
    McKay, Rana R.
    Garje, Rohan
    Bastos, Bruno R.
    Hoon, Dave S. B.
    Nabhan, Chadi
    Sledge, George W.
    Antonarakis, Emmanuel S.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [25] Tumor B7-H3 (CD276) Protein Expression, Smoking History, and Survival in Lung Adenocarcinoma Patients
    Inamura, Kentaro
    Yokouchi, Yusuke
    Kobayashi, Maki
    Sakakibara, Rie
    Ninomiya, Hironori
    Subat, Sophia
    Nagano, Hiroko
    Nomura, Kimie
    Okumura, Sakae
    Shibutani, Tomoko
    Ishikawa, Yuichi
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S802 - S802
  • [26] Pan-Cancer Interrogation of B7-H3 (CD276) as an Actionable Therapeutic Target Across Human Malignancies
    Miller, Carly D.
    Lozada, John R.
    Zorko, Nicholas A.
    Elliott, Andrew
    Makovec, Allison
    Radovich, Milan
    Heath, Elisabeth I.
    Agarwal, Neeraj
    Mckay, Rana R.
    Garje, Rohan
    Bastos, Bruno R.
    Hoon, Dave S. B.
    Orme, Jacob J.
    Sartor, Oliver
    VanderWalde, Ari
    Nabhan, Chadi
    Sledge, George
    Shenderov, Eugene
    Dehm, Scott M.
    Lou, Emil
    Miller, Jeffrey S.
    Hwang, Justin H.
    Antonarakis, Emmanuel S.
    CANCER RESEARCH COMMUNICATIONS, 2024, 4 (05): : 1369 - 1379
  • [27] CD276 (B7-H3) Maintains Proliferation and Regulates Differentiation in Angiogenic Function in Late Endothelial Progenitor Cells
    Son, YeonSung
    Kwon, Sang-Mo
    Cho, Je-Yoel
    STEM CELLS, 2019, 37 (03) : 382 - 394
  • [28] Comprehensive Analysis Reveals Distinct Immunological and Prognostic Characteristics of CD276/B7-H3 in Pan-Cancer
    Ding, Jinye
    Sun, Yaoqi
    Sulaiman, Zubaidan
    Li, Caixia
    Cheng, Zhongping
    Liu, Shupeng
    INTERNATIONAL JOURNAL OF GENERAL MEDICINE, 2023, 16 : 367 - 391
  • [29] SEX-SPECIFIC ROLES OFYAP1 AND CD276/B7-H3 IN MEDULLOBLASTOMA IMMUNE SUPPRESSION
    Abdelfattah, Nourhan
    Natarajan, Sivaraman
    Tran, Han Nhat
    Wong, Thomas
    Maldonado, Jose
    Borland, Hannah
    Mcminimy, Rachael
    Chen, Shu-hsia
    Camargo, Fernando
    Olson, James
    George, Joshy
    Yun, Kyuson
    NEURO-ONCOLOGY, 2024, 26
  • [30] B7-H3/CD276 Inhibitors: Is There Room for the Treatment of Metastatic Non-Small Cell Lung Cancer?
    Malapelle, Umberto
    Parente, Paola
    Pepe, Francesco
    Di Micco, Martina Concetta
    Russo, Alessandro
    Clemente, Celeste
    Graziano, Paolo
    Rossi, Antonio
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (24)