Successful treatment of lupoid cutaneous leishmaniasis with glucantime and topical trichloroacetic acid (a case report)

被引：6

作者：

Nilforoushudeh, Mohamad Ali ^{[1
]}

Sadeghian, Giti ^{[1
]}

Jaffary, Fariba ^{[1
,2
]}

Ziaei, Hengameh ^{[3
]}

Shirani-Bidabad, Liela ^{[1
]}

Mahzoni, Parvin ^{[4
]}

机构：

[1] Isfahan Univ Med Sci, Skin Dis & Leishmaniasis Res Ctr, Esfahan, Iran

[2] Isfahan Univ Med Sci, Dept Pharmacol & Toxicol, Sch Pharm & Pharmaceut Sci, Esfahan, Iran

[3] Isfahan Univ Med Sci, Sch Med, Esfahan, Iran

[4] Isfahan Univ Med Sci, Dept Pathol, Esfahan, Iran

来源：

KOREAN JOURNAL OF PARASITOLOGY | 2008年 / 46卷 / 03期

关键词：

Leishmanis tropica; cutaneous leishmaniasis; trichloroacetic acid;

D O I：

10.3347/kjp.2008.46.3.175

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Lupoid leishmaniasis is a unique form of cutaneous leishmaniasis characterized by unusual clinical features and a chronic relapsing course, mostly caused by infection with Leishmania tropica. In this clinical form, 1-2 yr after healing of the acute lesion, new papules and nodules appear at the margin of the remaining scar. Herein, we describe a case of this clinical form that was resistant to 2 courses of treatments: systemic glucantime and then a combination therapy with allopurinol and systemic glucantime. However, marked improvement was seen after a combination therapy with topical trichloroacetic acid solution (50%) and systemic glucantime, and there were no signs of recurrence after 1 yr of follow-up.

引用

页码：175 / 177

页数：3

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