Non-target and target screening of per- and polyfluoroalkyl substances in landfill leachate and impact on groundwater in Guangzhou, China

Landfills are the main destination of many urban wastes containing per-and polyfluoroalkyl substances (PFAS), and PFAS may leach out from the waste and contaminate the surrounding groundwater. Here we investigated the occur-rence of PFAS in leachate and surrounding groundwater from three landfills in Guangzhou, China by using a combined target and non-target approach. Non-target screening showed that a total of 651 PFAS with 96 classes were identified, including 17 legacy PFAS and 637 emerging PFAS. The quantitative target analysis of some PFAS revealed that the av-erage removal rate of PFAS from the raw leachates were ranged between 62 % and 99 %. Statistical analysis and source analysis suggested that landfill leachate was a major source of PFAS in the groundwater within the landfills and down-stream sites. The results from the combined target and non-target analyses demonstrated that PFAS in landfills could leach into the surrounding groundwater, and may affect the sustainable use of groundwater as a source of drinking water and pose a potential risk to human health.