Which individuals are at increased risk of pneumococcal disease and why? Impact of COPD, asthma, smoking, diabetes, and/or chronic heart disease on community-acquired pneumonia and invasive pneumococcal disease

被引:251
作者
Torres, Antoni [1 ]
Blasi, Francesco [2 ]
Dartois, Nathalie [3 ]
Akova, Murat [4 ]
机构
[1] Univ Barcelona, Serv Pneumol, Hosp Clin Barcelona, Inst Invest Biomed August Pi & Sunyer IDIBAPS,CIB, E-08036 Barcelona, Spain
[2] Univ Milan, Dept Pathophysiol & Transplantat, IRCCS Fdn Ca Granda Osped Maggiore, Milan, Italy
[3] Pfizer Vaccines, Med Affairs Europe, Paris, France
[4] Hacettepe Univ, Sch Med, Dept Infect Dis, Ankara, Turkey
关键词
OBSTRUCTIVE PULMONARY-DISEASE; POPULATION-BASED COHORT; LONG-TERM MORTALITY; OLDER-ADULTS; STREPTOCOCCUS-PNEUMONIAE; BACTEREMIC PNEUMONIA; GLYCEMIC CONTROL; ECONOMIC BURDEN; RECORD-LINKAGE; PRIMARY-CARE;
D O I
10.1136/thoraxjnl-2015-206780
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Pneumococcal disease (including community-acquired pneumonia and invasive pneumococcal disease) poses a burden to the community all year round, especially in those with chronic underlying conditions. Individuals with COPD, asthma or who smoke, and those with chronic heart disease or diabetes mellitus have been shown to be at increased risk of pneumococcal disease compared with those without these risk factors. These conditions, and smoking, can also adversely affect patient outcomes, including short-term and long-term mortality rates, following pneumonia. Community-acquired pneumonia, and in particular pneumococcal pneumonia, is associated with a significant economic burden, especially in those who are hospitalised, and also has an impact on a patient's quality of life. Therefore, physicians should target individuals with COPD, asthma, heart disease or diabetes mellitus, and those who smoke, for pneumococcal vaccination at the earliest opportunity at any time of the year.
引用
收藏
页码:984 / 989
页数:6
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