Iminophosphorane-mediated one-pot synthesis of 1,3,4-oxadiazole derivatives

被引：60

作者：

Ramazani, Ali ^{[1
]}

Souldozi, Ali ^{[2
]}

机构：

[1] Zanjan Univ, Dept Chem, POB 45195-313, Zanjan, Iran

[2] Islamic Azad Univ, Urmia Branch, Dept Chem, Orumiyeh, Iran

来源：

ARKIVOC | 2008年

基金：

美国国家科学基金会;

关键词：

(N-Isocyanimino)triphenylphosphorane; intramolecular aza-Wittig reaction; 1,3,4-oxadiazole; benzoic acid derivatives; iminophosphorane; isocyanide;

D O I：

10.3998/ark.5550190.0009.g22

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 4-substituted benzoic acid derivatives with (N-isocyanimino)-triphenylphosphorane proceeds smoothly at room temperature to afford the corresponding 2-aryl-1,3,4-oxadiazoles via an intramolecular aza-Wittig reaction in excellent yields under neutral conditions. The structures of the products were deduced from their IR, H-1 NMR, and C-13 NMR spectra, and mass spectrometry.

引用

页码：235 / 242

页数：8

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