Gene-specific regulation by general translation factors

被引：609
作者：
Dever, TE [1 ]
机构：
[1] NICHHD, Lab Gene Regulat & Dev, NIH, Bethesda, MD 20892 USA
来源：
CELL | 2002年 / 108卷 / 04期
关键词：
D O I：
10.1016/S0092-8674(02)00642-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Protein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, processing, or export. Recent studies have enhanced our understanding of the translation initiation process and helped elucidate how modifications of the general translational machinery regulate gene-specific protein production.
引用
收藏
页码：545 / 556
页数：12
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