Tobramycin-impregnated calcium sulfate pellets for the treatment of chronic osteomyelitis in children and adolescents

被引：31

作者：

Andreacchio, Antonio ^{[1
]}

Alberghina, Flavia ^{[1
]}

Paonessa, Matteo ^{[1
]}

Cravino, Mattia ^{[1
]}

De Rosa, Vincenzo ^{[2
]}

Canavese, Federico ^{[3
]}

机构：

[1] Regina Margherita Childrens Hosp, Dept Pediat Orthoped Surg, Turin, Italy

[2] Bellinzona & Valli Reg Hosp, Dept Pediat Orthoped, Bellinzona, Switzerland

[3] Univ Hosp Estaing, Dept Pediat Surg, 1 Pl Lucie & Raymond Aubrac, F-63003 Clermont Ferrand, France

来源：

JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B | 2019年 / 28卷 / 03期

关键词：

adolescents; calcium sulfate pellets; children; chronic osteomyelitis; single-stage surgery; BONE DEFECTS; SUBSTITUTE; MANAGEMENT; INFECTION;

D O I：

10.1097/BPB.0000000000000517

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The aim of this work was to evaluate the outcome and efficacy of treatment in a homogeneous group of skeletally immature patients with chronic osteomyelitis of the long bones managed by a combination of radical debridement and insertion of tobramycin-impregnated calcium sulfate pellets to fill the bone defect in a single-stage procedure. Between 2011 and 2016, 12 skeletally immature patients were treated surgically by the reported technique. Single-stage surgery using tobramycin-impregnated calcium sulfate pellets in association with systemic antibiotic therapy yields satisfactory outcomes in skeletally immature children presenting chronic osteomyelitis by reducing the risk of occurrence of comorbidities, hospital stays, and healthcare costs.

引用

页码：189 / 195

页数：7

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