Severity and impairment of allergic rhinitis in patients consulting in primary care

被引:219
作者
Bousquet, J
Neukirch, F
Bousquet, PJ
Gehano, P
Klossek, JM
Le Gal, M
Allaf, B
机构
[1] Univ Hosp Montpellier, Montpellier, France
[2] INSERM, U454, Montpellier, France
[3] INSERM, U408, Paris, France
[4] Assistance Publ Hosp Paris, Paris, France
[5] Univ Poitiers, Hosp Miletrie, Poitiers, France
[6] MAPI SA, CRO, Lyon, France
[7] Almirall France, Paris, France
关键词
allergic rhinitis; classification; ARIA; intermittent; persistent;
D O I
10.1016/j.jaci.2005.09.047
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background: Allergic rhinitis is a disease impairing quality of life, sleep, and work. A new classification for allergic rhinitis, Allergic Rhinitis and its Impact on Asthma (ARIA), has recently been proposed. Objective: To study the effect of allergic rhinitis using ARIA definitions to determine severity and duration. Methods: A total of 3052 patients consulting general practitioners for allergic rhinitis were studied. Patients were classified according to the 4 classes of ARIA. In all patients, quality of life (Rhinoconjunctivitis Quality-of-Life Questionnaire), sleep (Jenkins questionnaire), and work performance (Allergy-Specific Work Productivity and Activity Impairment questionnaire) were assessed. Results: Mild intermittent rhinitis was diagnosed in 11% of the patients, mild persistent rhinitis in 8%, moderate/severe intermittent rhinitis in 35%, and moderate/severe persistent rhinitis in 46%. The severity of rhinitis has more of an effect on quality of life, sleep, daily activities, and work performance than the duration of rhinitis. In moderate/severe rhinitis, more than 80% of patients report impaired activities, as opposed to only 40% with mild rhinitis. Conclusion: It seems that the term moderate/severe should be replaced by severe. A study in the general population is necessary, however, to assess the prevalence of the 4 ARIA classes of allergic rhinitis, especially in patients who are not consulting physicians for their symptoms.
引用
收藏
页码:158 / 162
页数:5
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