Use of lactoferrin in the newborn: where do we stand?

被引:6
作者
Sharma, Deepak [1 ]
Murki, Anuradha [2 ]
Murki, Srinivas [1 ]
Pratap, Oleti Tejo [1 ]
机构
[1] Fernandez Hosp, Dept Neonatol, Hyderabad 500029, Andhra Pradesh, India
[2] Kamineni Hosp, Dept Obstet & Gynaecol, Hyderabad, Andhra Pradesh, India
关键词
Anti-bacterial; anti-fungal; anti-viral; fungal sepsis; immunomodulation; lactoferrin; necrotizing enterocolitis; neonatal sepsis; LATE-ONSET SEPSIS; BOVINE LACTOFERRIN; HUMAN-MILK; ESCHERICHIA-COLI; ORAL LACTOFERRIN; GROWTH; IRON; PREVENTION; ADHERENCE; BACTERIAL;
D O I
10.3109/14767058.2014.968548
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Sepsis and necrotizing enterocolitis (NEC) cause significant morbidity and mortality in the newborn. Their ill effects persist in spite of appropriate and effective antibiotic therapy. Lactoferrin as an adjunct to antibiotics in the treatment of sepsis or NEC in the newborn may improve the clinical outcomes by enhancing the host defense and modulating the inflammatory response. This review focuses on the various aspects of lactoferrin use in the newborn.
引用
收藏
页码:1774 / 1778
页数:5
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