Understanding and addressing hepatitis C reinfection in the oral direct-acting antiviral era

被引：80

作者：

Falade-Nwulia, O. ^{[1
]}

Sulkowski, M. S. ^{[1
]}

Merkow, A. ^{[1
]}

Latkin, C. ^{[2
]}

Mehta, S. H. ^{[2
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Baltimore, MD 21218 USA

[2] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA

来源：

JOURNAL OF VIRAL HEPATITIS | 2018年 / 25卷 / 03期

关键词：

hepatitis C; men who have sex with men; people who inject drugs; reinfection; SUSTAINED VIROLOGICAL RESPONSE; HIV-POSITIVE MEN; VIRUS-INFECTION; HCV REINFECTION; RISK-FACTORS; LATE RELAPSE; SEX; PEOPLE; TRANSMISSION; CLEARANCE;

D O I：

10.1111/jvh.12859

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The availability of effective, simple, well-tolerated oral direct-acting antiviral (DAA) hepatitis C regimens has raised optimism for hepatitis C virus (HCV) elimination at the population level. HCV reinfection in key populations such as people who inject drugs (PWID) and HIV-infected men who have sex with men (MSM) however threatens the achievement of this goal from a patient, provider and population perspective. The goal of this review was to synthesize our current understanding of estimated rates and factors associated with HCV reinfection. This review also proposes interventions to aid understanding of and reduce hepatitis C reinfection among PWID and HIV-infected MSM in the oral direct-acting antiviral era.

引用

页码：220 / 227

页数：8

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