Selectively protected galactose derivatives for the synthesis of branched oligosaccharides

被引:11
|
作者
Lehtilä, RL
Lehtilä, JO
Roslund, MU
Leino, R
机构
[1] Biotie Therapies Corp, FIN-00710 Helsinki, Finland
[2] Abo Akad Univ, Dept Organ Chem, FIN-20500 Turku, Finland
关键词
galactose; protecting groups; monosaccharides; oligosaccharides;
D O I
10.1016/j.tet.2004.02.054
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis and characterization of several new anomerically pure galactose derivatives, based on simple and effective protective group manipulations of benzyl beta-D-galactopyranoside, are reported. The monosaccharides described contain selectively protected/deprotected hydroxyl functionalities at their 1,2,3,4- and 6-positions rendering them useful as building blocks for construction of branched oligosaccharides. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3653 / 3661
页数:9
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