Use of volatile compounds as a diagnostic tool for the detection of pathogenic bacteria

被引:51
作者
Tait, Emma [1 ]
Perry, John D. [2 ]
Stanforth, Stephen P. [1 ]
Dean, John R. [1 ]
机构
[1] Northumbria Univ, Fac Hlth & Life Sci, Dept Appl Sci, Newcastle Upon Tyne NE1 8ST, Tyne & Wear, England
[2] Freeman Rd Hosp, Dept Microbiol, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
关键词
Clinical sample; Detection; Diagnostic tool; Food sample; Gas chromatography (GC); Headspace (HS); Mass spectrometry (MS); Pathogenic bacteria; Solid-phase microextraction (SPME); Volatile compound (VC); SOLID-PHASE MICROEXTRACTION; CHROMATOGRAPHY-MASS SPECTROMETRY; GAS-LIQUID-CHROMATOGRAPHY; GRAM-NEGATIVE BACTERIA; ION MOBILITY SPECTROMETRY; LONG-CHAIN ALCOHOLS; MEXICAN FRUIT-FLIES; PSEUDOMONAS-AERUGINOSA; CLOSTRIDIUM-DIFFICILE; ORGANIC-COMPOUNDS;
D O I
10.1016/j.trac.2013.08.011
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The analysis of volatile compounds (VCs) generated by bacteria has been proposed as a possible alternative method for the identification of pathogenic bacteria. Further investigations into the VCs generated by many different species and strains of the same species are required alongside the use of consistent growth conditions and procedures throughout VC analysis. Consequently, the true potential of the detection of bacterial VCs as a diagnostic tool in the identification of pathogenic bacteria in clinical and food samples can be determined. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:117 / 125
页数:9
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