Immune and inflammatory pathways in NASH

被引：142
|
作者：
Ganz, Michal [1 ]
Szabo, Gyongyi [1 ]
机构：
[1] Univ Massachusetts, Med Sch, Dept Med, LRB208,364 Plantat St, Worcester, MA 01605 USA
来源：
HEPATOLOGY INTERNATIONAL | 2013年 / 7卷
关键词：
NAFLD; NASH; Inflammation; PAMPs; DAMPs; Immunity;
D O I：
10.1007/s12072-013-9468-6
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Immune and inflammatory pathways have a central role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Both the innate and adaptive immune systems contribute to the development of NAFLD. Pathogen-associated molecular patterns and danger-associated molecular patterns are known to activate a variety of pattern-recognition receptors that result in inflammation. The key features of the immune system and inflammatory pathways in the development of NAFLD are discussed in this review.
引用
收藏
页码：S771 / S781
页数：11
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