Immune and inflammatory pathways in NASH

被引：142

作者：

Ganz, Michal ^{[1
]}

Szabo, Gyongyi ^{[1
]}

机构：

[1] Univ Massachusetts, Med Sch, Dept Med, LRB208,364 Plantat St, Worcester, MA 01605 USA

来源：

HEPATOLOGY INTERNATIONAL | 2013年 / 7卷

关键词：

NAFLD; NASH; Inflammation; PAMPs; DAMPs; Immunity;

D O I：

10.1007/s12072-013-9468-6

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Immune and inflammatory pathways have a central role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Both the innate and adaptive immune systems contribute to the development of NAFLD. Pathogen-associated molecular patterns and danger-associated molecular patterns are known to activate a variety of pattern-recognition receptors that result in inflammation. The key features of the immune system and inflammatory pathways in the development of NAFLD are discussed in this review.

引用

页码：S771 / S781

页数：11