Ruthenium-Catalyzed Oxidative Dearomatization of N-Boc Indoles

被引：7

作者：

Chen, Xia ^{[1
]}

Zhou, Xiao-Yu ^{[1
]}

Feng, Xiu-Juan ^{[2
]}

Bao, Ming ^{[2
]}

机构：

[1] Liupanshui Normal Univ, Sch Chem & Mat Engn, Liupanshui 553004, Peoples R China

[2] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116023, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2021年 / 53卷 / 06期

关键词：

ruthenium; oxidative dearomatization; indoles; indolin-3-ones; sodium periodate; ALKALOIDS; OXYGENATION; 1ST;

D O I：

10.1055/s-0040-1706539

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ruthenium-catalyzed oxidative dearomatization ofN-Boc indoles for the synthesis of indolin-3-ones is described. TheN-Boc indoles can be transformed into indolin-3-ones in acetonitrile, using RuCl-(3)center dot 3H(2)O as catalyst and sodium periodate (1.5 equiv) as oxidant. Further, a possible mechanism has been proposed on the basis of control experiments.

引用

页码：1121 / 1126

页数：6

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