Viral capsid proteins (CPs) are characterized by their role in forming protective shells around viral genomes. However, CPs have additional and important roles in the virus infection cycles and in the cellular responses to infection. These activities involve CP binding to RNAs in both sequence-specific and nonspecific manners as well as association with other proteins. This review focuses on CPs of both plant and animal-infecting viruses with positive-strand RNA genomes. We summarize the structural features of CPs and describe their modulatory roles in viral translation, RNA-dependent RNA synthesis, and host defense responses. (C) 2013 Elsevier Inc. All rights reserved.
机构:
No Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA
No Illinois Univ, Dept Biol Sci, De Kalb, IL 60115 USANo Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA
Weber, Philipp H.
Bujarski, Jozef J.
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机构:
No Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA
No Illinois Univ, Dept Biol Sci, De Kalb, IL 60115 USA
Polish Acad Sci, Inst Bioorgan Chem, PL-61704 Poznan, PolandNo Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA
机构:
No Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA
No Illinois Univ, Dept Biol Sci, De Kalb, IL 60115 USANo Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA
Weber, Philipp H.
Bujarski, Jozef J.
论文数: 0引用数: 0
h-index: 0
机构:
No Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA
No Illinois Univ, Dept Biol Sci, De Kalb, IL 60115 USA
Polish Acad Sci, Inst Bioorgan Chem, PL-61704 Poznan, PolandNo Illinois Univ, Ctr Plant Mol Biol, De Kalb, IL 60115 USA