Pulse Pressure - Independent Predictor of Poor Early Outcome and Mortality following Ischemic Stroke

被引：18

作者：

Grabska, Katarzyna ^{[1
]}

Niewada, Maciej ^{[1
,2
]}

Sarzynska-Dlugosz, Iwona ^{[1
]}

Kaminski, Bogumil ^{[3
]}

Czlonkowska, Anna ^{[1
,2
]}

机构：

[1] Warsaw Med Univ, Inst Psychiat & Neurol, Dept Neurol 2, PL-02957 Warsaw, Poland

[2] Warsaw Med Univ, Dept Clin & Expt Pharmacol, PL-02957 Warsaw, Poland

[3] Warsaw Sch Econ, Inst Econometr, Dept Div Decis Anal & Support, Warsaw, Poland

来源：

CEREBROVASCULAR DISEASES | 2009年 / 27卷 / 02期

关键词：

Ischemic stroke; Pulse pressure; Blood pressure; BLOOD-PRESSURE; ARTERIAL STIFFNESS; HYPERTENSION; INDEXES; RISK;

D O I：

10.1159/000185611

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Pulse pressure (PP) in acute stroke may be related to the outcome. The link between PP in the first week following ischemic stroke and early outcome was assessed. Methods: We calculated mean PPs during the first 7 days after stroke onset in 1,677 patients. Poor outcome at hospital discharge was defined as a modified Rankin scale score of 3 or more points or death. Logistic regression was developed to evaluate PP as an independent predictor of early outcome. Results: For patients with poor outcomes the mean PP during the first week was higher than that for patients with non-poor outcomes. A logistic regression model confirmed that elevated mean PP was independently associated with poor outcome at discharge and 30-day mortality. Conclusion: Elevated PP during the acute phase of ischemic stroke is an independent predictor of poor early outcome at hospital discharge and 30-day mortality. Copyright (C) 2008 S. Karger AG, Basel

引用

页码：187 / 192

页数：6

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