Plant-based production of xenogenic proteins

被引：76
作者：
Hood, EE
Jilka, JM
机构：
[1] ProdiGene, Cell Biol, College Stn, TX 77845 USA
[2] ProdiGene, Mol Biol, College Stn, TX 77845 USA
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 1999年 / 10卷 / 04期
关键词：
D O I：
10.1016/S0958-1669(99)80069-X
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Foreign protein production in transgenic plants has been successful, from the generation of transgenic plant lines to the marketing of purified proteins. Antigenic proteins from disease organisms, monoclonal antibodies raised against antigens of disease organisms, and proteins with industrial process applications have been produced and tested. For vaccines, clinical trials in humans and feeding trials in animals are in progress to demonstrate their efficacy. For industrial proteins, high expression and downstream processing efficiency are key concerns, with application and test market trials in progress.
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页码：382 / 386
页数：5
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