Progress in Alzheimer's disease research in the last year

被引:13
|
作者
Galimberti, Daniela [1 ]
Scarpini, Elio [1 ]
机构
[1] Univ Milan, Dept Pathophysiol & Transplantat, Fdn Ca Granda, Neurol Unit,IRCCS Osped Policlin, I-20122 Milan, Italy
关键词
Alzheimer's disease; Biomarkers; Genetics; Risk factors; Imaging; Cerebrospinal fluid; Therapy; Disease-modifying drugs; CEREBROSPINAL-FLUID; BIOMARKER; DEMENTIA; TAU; DYSFUNCTION; BACE1; RISK; CSF;
D O I
10.1007/s00415-013-6921-3
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Alzheimer's disease (AD) is the most common cause of dementia in the elderly, with a prevalence of 5 % after 65 years of age, increasing to about 30 % in people aged 85 years or older. It is characterized by progressive cognitive impairment, including impaired judgment, decision-making and orientation, and in some cases accompanied by psycho behavioral disturbances or language impairment. Herein, we summarize and discuss the main articles describing novel findings in AD published over the last year, including clinical, therapeutic, and research issues.
引用
收藏
页码:1936 / 1941
页数:6
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