Bioactive acetogenins from the seeds of Annona atemoya

被引：24
|
作者：
Chang, FR [1 ]
Chen, JL [1 ]
Lin, CY [1 ]
Chiu, HF [1 ]
Wu, MJ [1 ]
Wu, YC [1 ]
机构：
[1] Kaohsiung Med Coll, Grad Inst Nat Prod, Kaohsiung 807, Taiwan
来源：
PHYTOCHEMISTRY | 1999年 / 51卷 / 07期
关键词：
Annona atemoya; Annonaceae; 12; 15-cis-squamostatin-D; 15-cis-squamostatin-A; artemoin-A; artemoin-B; artemoin-C; artemoin-D;
D O I：
10.1016/S0031-9422(99)00142-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Six new annonaceous acetogenins, 12,15-cis-squamostatin-D (1), 12,1 5-cis-squamostatin-A (2), artemoin-A (3), artemoin-B (4), artemoin-C (5) and artemoin-D (6), along with eleven known ones, were isolated from the seeds of Formosan Annona atemoya. The structures of these isolates were established on the basis of mass and related spectral evidence. All of them, except for four linear annonaceous acetogenins, exhibited potent cytotoxicity against Hep G(2), Hep 2,2,15, KB, CCM2 and CEM cancer cell lines. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：883 / 889
页数：7
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