Plasmid-mediated quinolone resistance in Escherichia coli strains isolated from animals in Turkey

被引：7
作者：
Mustak, H. Kaan [1 ]
Ica, Tuba [2 ]
Ciftci, Alper [3 ]
Diker, K. Serdar [1 ]
机构：
[1] Ankara Univ, Fac Vet Med, Dept Microbiol, TR-06110 Ankara, Turkey
[2] Dumlupinar Univ, Fac Arts & Sci, Dept Biol, Kutahya, Turkey
[3] Ondokuz Mayis Univ, Fac Vet Med, Dept Microbiol, Samsun, Turkey
来源：
ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI | 2012年 / 59卷 / 04期
关键词：
Animal; Escherichia coli; plasmid-mediated; quinolone-resistance; PREVALENCE; QNR; AAC(6')-IB-CR; EMERGENCE; GENE;
D O I：
10.1501/Vetfak_0000002535
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Chromosomal mutations and resistance genes transferred by plasmids are the main factors of quinolone resistance particularly in Escherichia coli strains isolated from both animals and humans. In this study a total of 259 E. coli strains were examined for the resistance to nalidixic acid and ciprofloxacin by agar dilution method and for the presence of qnrA, qnrB and qnrS genes that are known as plasmid-mediated quinolone resistance determinants by PCR. According to antimicrobial susceptibility tests 47 (50.0%) of 94 chicken, 3 (4.5%) of 66 sheep, 5 (9.6%) of 52 cattle and 3 (6.4%) of 47 dog E. coli strains were found to be resistant to ciprofloxacin. Among all plasmid-mediated quinolone resistance determinants that were investigated in this study, only qnrA gene was found in 5 (5.3%) of 94 E. coli chicken isolates. This is the sole report from Turkey that evaluated the plasmid-mediated quinolone resistance in animal isolates of E. coli strains.
引用
收藏
页码：255 / 258
页数：4
相关论文
共 23 条
[1]   Structure and distribution of pentapeptide repeats in bacteria [J].
Bateman, A ;
Murzin, AG ;
Teichmann, SA .
PROTEIN SCIENCE, 1998, 7 (06) :1477-1480
[2]  
Clinical and Laboratory Standards Institute, 2009, M07A8 CLSI
[3]   Plasmid-mediated quinolone resistance and β-lactamases in Escherichia coli from healthy animals from Nigeria [J].
Fortini, Daniela ;
Fashae, Kayode ;
Garcia-Fernandez, Aurora ;
Villa, Laura ;
Carattoli, Alessandra .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (06) :1269-1272
[4]   Plasmid-mediated quinolone resistance in non-Typhi serotypes of Salmonella enterica [J].
Gay, K ;
Robicsek, A ;
Strahilevitz, J ;
Park, CH ;
Jacoby, G ;
Barrett, TJ ;
Medalla, F ;
Chiller, TM ;
Hooper, DC .
CLINICAL INFECTIOUS DISEASES, 2006, 43 (03) :297-304
[5]  
Gyles C.L., 2010, PATHOGENESIS BACTERI, V4th, P267
[6]  
Holt J.G., 2000, Bergey's Manual of Determinative Bacteriology, V9th
[7]   Increased Prevalence of Plasmid-Mediated Quinolone Resistance Determinants in Chicken Escherichia coli Isolates from 2001 to 2007 [J].
Huang, Si-Yang ;
Dai, Lei ;
Xia, Li-Ning ;
Du, Xiang-Dang ;
Qi, Yong-Hua ;
Liu, He-Bing ;
Wu, Cong-Ming ;
Shen, Jian-Zhong .
FOODBORNE PATHOGENS AND DISEASE, 2009, 6 (10) :1203-1209
[8]   Prevalence of plasmid-mediated quinolone resistance [J].
Jacoby, GA ;
Chow, N ;
Waites, KB .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (02) :559-562
[9]   Plasmid-mediated quinolone resistance determinants qnr and aac(6′)-Ib-cr in Escherichia coli and Klebsiella spp. from Norway and Sweden [J].
Karah, Nabil ;
Poirel, Laurent ;
Bengtsson, Stina ;
Sundqvist, Martin ;
Kahlmeter, Gunnar ;
Nordmann, Patrice ;
Sundsfjord, Arnfinn ;
Samuelsen, Orjan .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2010, 66 (04) :425-431
[10]   Characterization of plasmid-mediated quinolone resistance by the qnrS gene in Escherichia coli isolated from healthy chickens and pigs [J].
Kuo, H. -C. ;
Chou, C. -C. ;
Tu, C. ;
Gong, S. -R. ;
Han, C. -L. ;
Liao, J. -W. ;
Chang, S. -K. .
VETERINARNI MEDICINA, 2009, 54 (10) :473-482
123