Fabrication of Calixarene Based Protein Scaffold by Electrospin Coating for Tissue Engineering

被引：15

作者：

Cagil, Esra Maltas ^{[1
,2
]}

Ozcan, Fatih ^{[3
,4
]}

Ertul, Seref ^{[3
]}

机构：

[1] Selcuk Univ, Fac Pharm, TR-42075 Konya, Turkey

[2] Selcuk Univ, Int Ctr Excellence Pharm, TR-42075 Konya, Turkey

[3] Selcuk Univ, Dept Chem, TR-42075 Konya, Turkey

[4] Adv Technol Res & Applicat Ctr, TR-42075 Konya, Turkey

来源：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2018年 / 18卷 / 08期

关键词：

Nanofiber; Albumin; Protein; Calixarene; Electrospin Coating; Fluorescence; Nanotechnology; Biomedical; Scaffold; Tissue Engineering; Pharmaceuticals; MESOPOROUS SILICA NANOPARTICLES; DRUG-DELIVERY; BIOSENSING APPLICATIONS; BIOMEDICAL APPLICATIONS; XANTHINE DETECTION; BINDING; NANOCOMPOSITE; NANOMATERIALS; DESIGN; SYSTEM;

D O I：

10.1166/jnn.2018.15381

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, calixarene was synthesized by using different functional groups as p-tert-butyl-Calix[4] arene ester and amides. Calixarene nanofibers were produced by electrospin coating. Protein immobilization onto the calixarene nanofibers was carried out with human serum albumin (HSA). The maximum amount of binding on produced three different calixarene nanofibers (DE, 2-AMP and 3-AMP) was compared by using a fluorescence technique for protein analysis. Result showed that maximum binding amount was found to be as 177.85 mg cm(-2) for 3-AMP surface. The protein binding was also characterized by using SEM, TEM, AFM and FT-IR. From obtained results, calixarene-albumin nanofiber was also fabricated by spin coating using 3-AMP which has ability max binding of protein.

引用

页码：5292 / 5298

页数：7

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