The importance of organ geometry and boundary constraints for planning of medical interventions

被引:56
作者
Misra, S. [1 ]
Macura, K. J. [2 ]
Ramesh, K. T. [1 ]
Okamura, A. M. [1 ]
机构
[1] Johns Hopkins Univ, Dept Mech Engn, Baltimore, MD 21218 USA
[2] Johns Hopkins Med Inst, Dept Radiol & Radiol Sci, Baltimore, MD 21205 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
Anatomy; Biopsy; Brachytherapy; Elasticity; Finite element modeling; Needle insertion; Path planning; Prostate; NEEDLE INSERTION; SURGICAL SIMULATION; REGISTRATION;
D O I
10.1016/j.medengphy.2008.08.002
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Realistic modeling of medical interventions involving tool-tissue interactions has been considered to be a key requirement in the development of high-fidelity simulators and planners. Organ geometry, soft-tissue constitutive laws, and boundary conditions imposed by the connective tissues surrounding the organ are some of the factors that govern the accuracy of medical intervention planning. In this study it is demonstrated that, for needle path planning, the organ geometry and boundary constraints surrounding the organ are the most important factors influencing the deformation. As an example, the procedure of needle insertion into the prostate (e.g. for biopsy or brachytherapy) is considered. Image segmentation is used to extract the anatomical details from magnetic resonance images, while object-oriented finite element analysis (OOF) software is used to generate finite element (FE) meshes from the segmented images. Two-dimensional FE simulations that account for complex anatomical details along with relative motion between the prostate and its surrounding structure using cohesive zone models are compared with traditional simulation models having simple organ geometry and boundary constraints. Nodal displacements for these simpler models were observed to be up to 14 times larger than those obtained from the anatomically accurate models. (C) 2008 IPEM. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:195 / 206
页数:12
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