Recent Advances of Silver-Based Coordination Polymers on Antibacterial Applications

被引:73
作者
Zhang, Wenfeng [1 ,2 ]
Ye, Gaomin [1 ,2 ]
Liao, Donghui [1 ,2 ]
Chen, Xuelin [1 ]
Lu, Chengyu [1 ]
Nezamzadeh-Ejhieh, Alireza [3 ]
Khan, M. Shahnawaz [4 ]
Liu, Jianqiang [1 ]
Pan, Ying [1 ,2 ]
Dai, Zhong [1 ]
机构
[1] Guangdong Med Univ, Key Lab Res & Dev New Med Mat, Sch Pharm, Guangdong Prov Key Lab Res & Dev Nat Drugs, Dongguan 523808, Peoples R China
[2] Guangdong Med Univ, Dongguan Affiliated Hosp 1, Dongguan 523808, Peoples R China
[3] Islamic Azad Univ, Chem Dept, Shahreza Branch, Shahreza 31186145, Iran
[4] Aligarh Muslim Univ, Dept Chem, Aligarh 202002, Uttar Pradesh, India
来源
MOLECULES | 2022年 / 27卷 / 21期
关键词
metal-organic frameworks; anti-bacterial effect; anti-bacterial mechanism; silver; METAL-ORGANIC-FRAMEWORK; CRYSTAL-STRUCTURES; DRUG-DELIVERY; ANTIMICROBIAL ACTIVITY; PHOTODYNAMIC THERAPY; NANOPARTICLES; EFFICIENT; MECHANISM; CANCER; SERIES;
D O I
10.3390/molecules27217166
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
With the continuous evolution of bacteria and the constant use of traditional antibiotics, the emergence of drug-resistant bacteria and super viruses has attracted worldwide attention. Antimicrobial therapy has become the most popular and important research field at present. Coordination Polymer (CP) and/or metal-organic framework (MOF) platforms have the advantages of a high biocompatibility, biodegradability, and non-toxicity, have a great antibacterial potential and have been widely used in antibacterial treatment. This paper reviewed the mechanism and antibacterial effect of three typical MOFs (pure Ag-MOFs, hybrid Ag-MOFs, and Ag-containing-polymer @MOFs) in silver-based coordination polymers. At the same time, the existing shortcomings and future views are briefly discussed. The study on the antibacterial efficacy and mechanism of Ag-MOFs can provide a better basis for its clinical application and, meanwhile, open up a novel strategy for the preparation of more advanced Ag-contained materials with antibacterial characteristics.
引用
收藏
页数:27
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