Classification and evolutionary trends of icosahedral viral capsids

被引：9
作者：
Kerner, Richard [1 ]
机构：
[1] Univ Paris 06, CNRS, LPTMC, UMR 7600, F-75005 Paris, France
来源：
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE | 2008年 / 9卷 / 3-4期
关键词：
viral capsid classification; self-organized agglomeration; symmetry;
D O I：
10.1080/17486700802167728
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A classification of icosahedral viral capsids is proposed. We show how the self-organization of capsids during their formation implies a definite composition of their elementary building blocks. The exact number of hexamers with three different admissible symmetries is related to capsids' sizes, labelled by their T-numbers. Simple rules determining these numbers for each value of T are deduced and certain consequences concerning the probabilities of mutations and evolution of viruses are discussed.
引用
收藏
页码：175 / 181
页数：7
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