EPIDEMIOLOGY Interpreting studies of interactions between RA risk factors

被引：9
|
作者：
Karlson, Elizabeth W. [1 ]
Costenbader, Karen H. [1 ]
机构：
[1] Brigham & Womens Hosp, Div Rheumatol Immunol & Allergy, Clin Sci Sect, Boston, MA 02115 USA
来源：
NATURE REVIEWS RHEUMATOLOGY | 2010年 / 6卷 / 02期
关键词：
SHARED EPITOPE ALLELES; RHEUMATOID-ARTHRITIS; SMOKING; HLA-DRB1; PEPTIDE; PTPN22; GENE;
D O I：
10.1038/nrrheum.2009.276
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Interactions between HLA and PTPN22 genotypes and smoking have been implicated in overall susceptibility to rheumatoid arthritis as well as the incidence of particular disease phenotypes in case–control and case-only studies. As recent epidemiological evidence shows, deciphering these interactions demands consideration of the analytical approach used.
引用
收藏
页码：72 / 73
页数：2
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