Novel diagnostics for point-of-care bacterial detection and identification

被引：44

作者：

Reali, Savannah ^{[1
]}

Najib, Elias Y. ^{[1
]}

Balazs, Krisztina E. Treuerne ^{[1
]}

Tan, Adeline Chern Hui ^{[1
]}

Varadi, Linda ^{[2
]}

Hibbs, David E. ^{[1
]}

Groundwater, Paul W. ^{[1
]}

机构：

[1] Univ Sydney, Sch Pharm, Camperdown Campus, Sydney, NSW 2006, Australia

[2] CSIRO Mfg, Normanby Rd, Clayton, Vic 3168, Australia

来源：

RSC ADVANCES | 2019年 / 9卷 / 37期

关键词：

INFECTIOUS-DISEASES; MAGNETIC NANOPARTICLES; STAPHYLOCOCCUS-AUREUS; BIOSENSORS; SYSTEM; GOLD; PCR; ANTIBIOTICS; SENSITIVITY; PLATFORM;

D O I：

10.1039/c9ra03118a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In addition to limiting the effectiveness of antimicrobial agents, antimicrobial resistance (AMR) is a significant global health concern as it is responsible for significant mortality/morbidity and increased economic burdens on healthcare systems. Diagnostic tests have been suggested as a means of prolonging the effectiveness of current antimicrobials; culture and other conventional diagnostics are hindered in their practicality as they are time- and labour intensive to perform. Point-of-care (POC) testing is performed near where the patient is being treated and can provide timely results that allow evidence based clinical interventions to be made. This review aims to outline the chemical principles behind some novel and emerging diagnostic techniques which have the required speed, simplicity, effectiveness and low-cost for incorporation into POC devices which can be used to inform and optimize antimicrobial use.

引用

页码：21486 / 21497

页数：12

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