Cyclodextrin dimer derivatives used as stationary phase for capillary gas chromatography

Four cyclodetrin dimer derivatives were synthesized by linking two single cyclodextrin derivatives with difunctional spacer at the primary side of cyclodetrin. The separation properties of these cyclodextrin dimer derivatives as CGC stationary phases were investigated and compared with those of the unbridged native cyclodextrin derivative. The results show that two recognition sites and one link spacer of these cyclodextrin dimer derivatives cooperate in separation and affect the separation of disubstituted benzene positional isomers.