A nano-Ni based ultrasensitive nonenzymatic electrochemical sensor for glucose: Enhancing sensitivity through a nanowire array strategy

被引：378

作者：

Lu, Li-Min ^{[1
]}

Zhang, Li ^{[1
]}

Qu, Feng-Li ^{[1
,2
]}

Lu, Hai-Xia ^{[1
]}

Zhang, Xiao-Bing ^{[1
]}

Wu, Zai-Sheng ^{[1
]}

Huan, Shuang-Yan ^{[1
]}

Wang, Qiu-An ^{[1
]}

Shen, Guo-Li ^{[1
]}

Yu, Ru-Qin ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chem Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

[2] Qufu Normal Univ, Coll Chem Sci, Key Lab Life Organ Anal, Qufu 273165, Shandong, Peoples R China

来源：

BIOSENSORS & BIOELECTRONICS | 2009年 / 25卷 / 01期

基金：

湖南省自然科学基金; 中国国家自然科学基金;

关键词：

Ni nanowire arrays; Glucose; Amperometry; Nonenzymatic sensor; Electropolymerization; POTENTIAL AMPEROMETRIC DETECTION; GLASSY-CARBON ELECTRODE; FLOW-INJECTION ANALYSIS; ELECTROCATALYTIC OXIDATION; OXIDE NANOPARTICLES; PASTE ELECTRODE; PLATINUM; ALKALINE; ENZYME; BIOSENSORS;

D O I：

10.1016/j.bios.2009.06.041

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Highly ordered Ni nanowire arrays (NiNWAs) were synthesized for the first time using a template-directed electropolymerization strategy with a nanopore polycarbonate (PC) membrane template, and their morphological characterization were examined by scanning electron microscopy (SEM) and transmission electron microscope (TEM). A NiNWAs based electrode shows very high electrochemical activity for electrocatalytic oxidation of glucose in alkaline medium, which has been utilized as the basis of the fabrication of a nonenzymatic biosensor for electrochemical detection of glucose. The biosensor can be applied to the quantification of glucose with a linear range covering from 5.0 x 10(-7) to 7.0 x 10(-3) M, a high sensitivity of 1043 mu A mM(-1) cm(-1), and a low detection limit of 1 x 10(-7) M. The experiment results also showed that the sensor exhibits good reproducibility and long-term stability, as well as high selectivity with no interference from other oxidable species. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：218 / 223

页数：6

共 40 条

[1] INSITU INFRARED STUDIES OF GLUCOSE-OXIDATION ON PLATINUM IN AN ALKALINE-MEDIUM [J].