Influenza vaccine effectiveness among 50-64-year-old persons during a season of poor antigenic match between vaccine and circulating influenza virus strains: Colorado, United States, 2003-2004

被引：68

作者：

Herrera, Guillermo A. ^{[1
]}

Iwane, Marika K. ^{[1
]}

Cortese, Margaret ^{[1
]}

Brown, Cedric ^{[1
]}

Gershman, Ken ^{[1
]}

Shupe, Alyson ^{[1
]}

Averhoff, Francisco ^{[1
]}

Chaves, Sandra S. ^{[1
]}

Gargiullo, Paul ^{[1
]}

Bridges, Carolyn B. ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Viral Vaccine Preventable Dis Branch, Natl Immunizat Program, Epidemiol & Surveillance Div, Atlanta, GA 30333 USA

来源：

VACCINE | 2007年 / 25卷 / 01期

关键词：

influenza; vaccine effectiveness; influenza vaccine; laboratory-confirmed influenza; influenza-related hospitalizations; influenza vaccine mismatch;

D O I：

10.1016/j.vaccine.2006.05.129

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During the 2003-2004 influenza season, we conducted a case-control study of influenza vaccine effectiveness (VE) among Colorado residents aged 50-64 years. Cases (n = 330) were identified from laboratory-confirmed influenza reports to the Colorado Department of Public Health and Environment (CDPHE). Controls (n = 1055) were recruited by random-digit dial telephone survey. VE was 60% (43-72%) and 48% (21-66%) among those without and with high-risk medical conditions, respectively. VE was 90% (68-97%) and 36% (0-63%) against influenza-related hospitalization for persons without and with high-risk conditions, respectively. Published by Elsevier Ltd.

引用

页码：154 / 160

页数：7

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[21] Regulation of Experimental Autoimmune Encephalomyelitis by CD4+, CD25+ and CD8+ T cells:: analysis using depleting antibodies [J].