Comparison of nitroglycerin lingual spray and sublingual tablet on time of onset and duration of brachial artery vasodilation in normal subjects

被引：60

作者：

Ducharme, A ^{[1
]}

Dupuis, J ^{[1
]}

McNicoll, S ^{[1
]}

Harel, F ^{[1
]}

Tardif, JC ^{[1
]}

机构：

[1] Montreal Heart Inst, Res Ctr, Dept Med, Div Cardiol, Montreal, PQ H1T 1C8, Canada

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1999年 / 84卷 / 08期

关键词：

D O I：

10.1016/S0002-9149(99)00478-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study compared the rapidity of onset, the magnitude, and the duration of action of 2 shore-acting nitroglycerin preparations using high-resolution brachial ultrasound. Both sublingual tablet and lingual spray formulations caused maximal vasodilation at 3 minutes; however, the spray provided faster (at 2 minutes), greater, and more prolonged (15 minutes) vasodilation than the tablet.

引用

页码：952 / +

页数：4

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